Sinoway Industrial Co., Ltd

Date: 9th May 2016
Epirubicin HCL
Sinoway Industrial Co.,Ltd is a famous China epirubicin hcl manufacturer and supplier,Website:http://www.sinoway-chem.com, welcome to buy GMP and EP epirubicin hcl from us and check the price with us.Basic information of Epirubicin HCL:NameEpirubicin HCLAliasEpirubicin hydrochloride; (8s-cis)-rochlorid;4'-epi-adriamycinhydrochloride;5,12-naphthacenedione,10-((3-amino-2,3,6-trideoxy-alpha-l-arabino-hexopyranosy;8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-l)oxy)-hyd;EPIRUBICIN HYDROCHLORIDE EP STANDARD;EpirubicinHc,LEp5,;Adrial;Ellence, Farmorubicin, PharmorubicinCAS NO.56390-09-1Molecular FormulaC27H30ClNO11Molecular Weight579.9802Quality StandardEP7.0Package Size1g/bag;10g/bag or other customized packagesUse of Epirubicin HCL:Antibiotic antitumor agent. Inhibits the synthesis and function of DNA (IC 50 = 62.7 ? M in rat glioblastoma cell lines) and inhibits the relaxing property of topoisomerase II.COA of Epirubicin HCL :TestSpecificationAppearanceAn orange-red powderSolubilitySoluble in water or in methanol, slightly soluble in anhydrous ethanol, practically insoluble in acetone.IdentificationA) IR absorption spectrum be consistent with that of its CRS.B) HPLC: The retention time of principal peak is similar in that of its reference peak.C) Exhibits the precipitate reaction of Ag+.PH4.0-5.5WaterNMT 4.0%Bacterial endotoxinsNMT 1.1 IU/mgRelated substancesDoxorubicino NMT 1.0%Doxorubicin NMT 1.0%Impurity B: NMT 0.5%Impurity D: NMT 0.5%Impurity E: NMT 0.5%Impurity F: NMT 0.5%Impurity G: NMT 0.5%Any other unknown impurity: NMT 0.1%Total impurities: NMT 2.0%Assay97.0% ~ 102.0%ConclusionConforms to the requirements of EP7.0 standards.
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